DNA sequencing hopes of each living creature on Earth a step forward with the announcement of plans sequence of at least 10,000 genomes represent each major clade of plants and eukaryotic microbes. Chinese giant BGI sequencing and the National Bank of China Gene (CNGB) yesterday held a workshop at the International Botanical Congress, held this week in the hometown of BGI in Shenzhen to discuss what they call 10KP plan. Over 250 scientists
from plants participated in the discussions and "are eager to go," said Gane Ka-Shu Wong genomicist and bioinformatics at the University of Alberta, Edmonton.
10KP plan is a key element of the BioGenome Earth Project (EBP), a demanding and always raw sequence data that changes at least 1.5 million eukaryotic species, starting with detailed sequences a member of each family 9,000 eukaryotes. The attempt to sequenge the plant moves somewhat faster than other aspects of PAAS "because scientists are more cooperative with plants," says Wong jokingly.10KP Card also builds a project about 1000 plants (1KP) transcriptome above. These efforts, launched in 2012 and just before graduation, were also led by BGI, where Wong is Associate Director."One thing we were concentrating on (for 1KP) was the phylogenetic variety palpation, not just from cultures and model organisms," said Wong. 10KP track this strategy. Transcriptome project led to more than 50 articles, the general impending publication synthesis. A large part of the discussion focused on the development of the plants. One of the surprises is that important transcription factors that have evolved have been thought to colonized as land plants habitats back to green algae, said Michael Melkonian, a botanist at the University of Cologne in Germany. The detection of green algae has also introduced new proteins sensitive to light as neuroscientists now use to investigate how neurons interact and better understand the different neurological function.While the project was expressed by an organism 10KP 1KP transcriptome or messenger RNA produce completely new sequences in the genome. And scientists expect a gold mine even more basic ideas and economic benefits. The 10KP project "1KP on steroids is", says Douglas Soltis, a plant biologist at the Natural History Museum of the University of Florida in Gainesville, Florida. He added that a "wonderful thing" about the project is to create reference genomes "which many researchers are studying plants without model systems," he said. The project will also address "fundamental questions about the evolution of plants, a unique opportunity to address," said Stephen Smith, an evolutionary biologist at the University of Michigan, Ann Arbor. It is expected that the objectives of the study will include the role of genome duplication, the correlation between genomic and morphological changes, and how development rates have changed over time.A challenge that Smith aims to develop is the need to develop new ways to analyze and sequencing information. "The tools and existing methods are not able to handle the extraordinary volume of data," he said. Wong said another bottleneck will process the necessary formalities with the legal requirements of the border facilities in physical boundaries and the Nagoya Protocol, an international agreement respected to ensure the balanced and fair sharing of genetic resources. In addition, sample collection is easier than for other areas of genetics. "You do not have to chase certain animals, usually can not go to a botanical garden," says Wong.Xu Xun, who heads the technical development of BGI, said the company and GBSC cover the cost of sequencing, but "scientists must take their own resources to take samples and analyze them. "As for the time, Wong said, they hope the next two years to collect samples and" we hope to complete the sequencing and analysis in 5 years. ""We are ready to start the episode yesterday," Wong said. And scientists are worried plants. According to yesterday's meeting in Shenzhen, "many people have approached people who were already sending samples," he said.